DYSLIPIDEMIA AND PERIPHERAL PREDIABETIC NEUROPATHY
نویسندگان
چکیده
منابع مشابه
Dyslipidemia-Induced Neuropathy in Mice
OBJECTIVE Neuropathy is a frequent and severe complication of diabetes. Multiple metabolic defects in type 2 diabetic patients result in oxidative injury of dorsal root ganglia (DRG) neurons. Our previous work focused on hyperglycemia clearly demonstrates induction of mitochondrial oxidative stress and acute injury in DRG neurons; however, this mechanism is not the only factor that produces neu...
متن کاملRole of insulin signaling impairment, adiponectin and dyslipidemia in peripheral and central neuropathy in mice
One of the tissues or organs affected by diabetes is the nervous system, predominantly the peripheral system (peripheral polyneuropathy and/or painful peripheral neuropathy) but also the central system with impaired learning, memory and mental flexibility. The aim of this study was to test the hypothesis that the pre-diabetic or diabetic condition caused by a high-fat diet (HFD) can damage both...
متن کاملThe association of dyslipidemia and peripheral diabetic neuropathy: the influence of urea
Methodology Ninety consecutive patients at a university hospital in Manaus, Amazonas were included in this study. Eighty-six (95.6%) had type 2 diabetes, 66.7% were female, mean age was 56.2±12.8 yrs.-old and mean time of diabetes diagnosis was 11.5±9.5 yrs. They were evaluated using Michigan Neuropathy Screening Instrument (MNSI) and the clinical component of the Michigan Diabetic Neuropathy S...
متن کاملPrevalence of Peripheral Neuropathy in Diabetic Patients
Abstract Objective: Diabetic peripheral neuropathy is the main risk factor of diabetic foot ulcer and its early diagnosis is important to prevent limb amputation. We assessed the prevalence of peripheral neuropathy in diabetic patients. Materials and methods: This cross-sectional study was performed on 352 randomly selected diabetic patients using a standardized questionnaire including age, g...
متن کاملPeripheral neuropathy.
Patients presenting with symptoms of peripheral neuropathy are commonplace in the practice of generalist physicians, office based or hospitalists. Although there are at least a thousand different causes for peripheral neuropathy, the majority of patients can be properly diagnosed (and managed) based on framing the diagnostic possibilities within one of six typical scenarios. The case presentati...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.1035.3